
Basically any modern games (or any software for that matter) that doesn't allow any type of free saving at any given point could benefit from this.
Basically, pause whatever game you're playing using the standard ctrl-alt-delete to bring up Windows task manager, Hibernate your system, then using some ghosting software (like Norton Ghost) create a "savestate" of the content of your Harddrive (which will include the RAM content saved by the OS).
I realise it's highly impracticable in real day to day usage but in a few obscure and very rare cases I think it could be potentially usefull. For example, you could create a "savestate" in bsnes, if you wanted to reproduce a particularly rare bug that only occurs after like...10 hours of gameplay or something and the game itself had no native saves.